Rate Determination Step.

It can be made applicable to exaggerate test conditions of short duration provided the function can be linearised in accordance with chemical kinetic reaction orders.Example of color stability of a multidose sulfonamide preparation can be done by observing the plot of the logarithms of the rate of decrease in absorbance of extracted color per hour against the reciprocal of absolute temperature. By the use of colorimetric measurements of the sample subjected to thermally accelerated degradation, it is possible to predict the color stability of the preparation at room temperature.